Quarterback J.J. McCarthy got some unfortunate news moments before his Vikings debut on Monday - as one of the team's top offensive linemen was ruled out through injury.
Left tackle Christian Darrisaw was announced as an inactive for the NFC North clash against the Bears with a knee injury.
The 26-year-old suffered a torn ACL and MCL last October in a game at the Rams.
Darrisaw is expected to be replaced by Justin Skule on the offensive line.
Minnesota will also be without veteran safety Harrison Smith due to an undisclosed illness, while the Bears have some injury issues of their own as well.
Starting defensive backs Jaylon Johnson and Kyler Gordon are both out for Chicago's season opener against Minnesota, while linebacker T.J. Edwards has also been sidelined by a hamstring injury.
J.J. McCarthy will be without one of his top offensive linemen in his NFL debut
Left tackle Christian Darrisaw is still recovering from a knee injury after tearing his ACL and MCL
Darrisaw was limited to just seven games last season after injuring himself against the Rams on October 24.
Nonetheless, he practiced fully on Saturday and was listed as questionable on the team's injury report heading into their Week 1 matchup against the Bears.
McCarthy, 22, is set to make his first regular season start on Monday more than a year after being drafted No. 10 overall by Minnesota.
He missed the entirety of his rookie season with a torn meniscus in his right knee, and watched from the sideline as Sam Darnold had a career year for the Vikings.
However, the Vikings allowed Darnold to sign with the Seahawks in free agency and committed to McCarthy as their quarterback of the future.